Research News 4
Research News
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Women Making AIDS History
Women scientists and advocates, such as amfAR’s Dr. Mathilde Krim and Elizabeth Taylor, have been a driving force in the fight against AIDS.
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Early Treatment No Barrier to Reservoir Formation
HIV too quickly creates pools of actively and latently infected T cells for antiretroviral therapy to block viral persistence.
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Confirmed: Düsseldorf Patient Cured of HIV
Researchers have confirmed that a 53-year-old man in Germany named Marc, formerly known only as the Düsseldorf patient, has been cured of HIV via a stem cell transplant.
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A Shared Passion for HIV Cure Research
In this interview, amfAR grantees Dr. Xu Yu and Dr. Mathias Lichterfeld, who are married, discuss their research interests and share their insights.
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Footprints, Signatures, and Survival Factors
Aiming to identify HIV reservoirs, researchers use next-generation gene sequencing to detect markers on memory CD4 T cells.
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The Road Ahead
HIV cure researchers convened a three-day workshop to share updates on HIV reservoirs and strategies aimed at achieving viral eradication.
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How Do Some People Control HIV Without Antiretroviral Therapy?
Identifying mechanisms that allow elite controllers to suppress HIV in the absence of ART may aid in vaccine development.
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Blocking T-Cell Growth: Will It Shrink the Reservoir?
A small cure trial explored the possibility that suppressing T-cell proliferation might reduce the HIV reservoir.
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Dr. Lishomwa “Lish” Ndhlovu Takes the Lead
amfAR’s newly appointed Scientific Advisory Committee Chair discusses the power of collaboration and creating the space for unexpected breakthroughs in HIV cure research.
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A Step Toward Eliminating Reservoir Cells?
Researchers identify markers on T cells with increased latent HIV in order to target them for elimination.
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Meet the London Patient: Adam Castillejo
The second person cured of HIV talks to amfAR’s Dr. Rowena Johnston about advocacy and AIDS research..
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amfAR Awards $1.5 Million to Researchers Targeting the HIV Reservoir
amfAR’s new grants support HIV cure research using mRNA and gene-editing technologies, and souped-up natural killer cells, to target the HIV reservoir.
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The Issue of Tissue: Getting to the Source of the HIV Reservoir
Researchers emphasize a full characterization of the HIV reservoir needs to focus on tissue sites, not only blood, in the search for a cure.
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Improving HIV Latency-Reversing Strategies
Laying the groundwork for a cure, researchers investigate a potent “pathogen-activated” antiretroviral therapy strategy to eliminate HIV reservoirs.
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Developing the Next Generation of COVID-19 Vaccines
Researchers have again parlayed HIV research to COVID-19 to develop a nanoparticle mRNA-based vaccine platform to address SARS-CoV-2 variants.